Elderberry: Natural Medicine for Colds, Flus, Allergies & More

By Dr. Josh Axe, DC, DMN, CNS

August 27, 2018

Looking for a natural remedy that has a very long history of medicinal use? There’s evidence that the elderberry may have been cultivated by prehistoric man. There are also recipes for elderberry-based medications dating back to Ancient Egypt.

However, most historians typically trace its healing abilities back to Hippocrates, the ancient Greek known as the “father of medicine,” who described the plant as his “medicine chest” because of the wide array of health concerns it seemed to cure. (1) Whether we’re talking cavemen, ancient Egyptians or ancient Greeks, this natural remedy definitely goes way back, so it’s no wonder it’s known as one of the top antiviral herbs on the planet.

Health benefits of the elder plant include naturally improving colds, the flu, sinus issues, nerve pain, inflammation, chronic fatigue, allergies, constipation and even cancer. (2) When used within the first 48 hours of onset of symptoms, the extract has actually been found to reduce the duration of the flu with symptoms being relieved on an average of four days earlier. (3) During the 1995 Panama flu epidemic, the government actually employed the use of the elderberry to fight the flu.

I’m sure you’re getting the picture that this medicinal berry is a real powerhouse for good health. Let’s examine exactly why.

What Is Elderberry?

Sambucus is a genus of flowering plants in the family Adoxaceae. The different species of Sambucus are commonly called elderberry or elder. The berries and flowers of the elder plant are used as medicine. Elderberry is native to Europe, Africa and parts of Asia, but it’s become common in the U.S. It has deciduous leaves, white flowers (elderflowers) and berries that turn from green to red to black when ripe. Elder is commonly found growing in woodlands and hedgerows.

Sambucus nigra is the full scientific name of the most common variety used for medicinal purposes. Sambucus nigra is the species on which the majority of scientific research has been conducted. It’s a deciduous tree growing up to 32 feet tall with cream-white flowers and blue-black berries. Other common names for Sambucus nigra include black elder, European elder, European elderberry and European black elderberry. The elderberry bush or elder tree yields the berries that are commonly used in syrups, jams and wine, among other medicinal and culinary delights.

European elder flowers contain approximately 0.3 percent of an essential oil composed of free fatty acids and alkanes. The triterpenes alpha- and beta-amyrin, ursolic acid, oleanolic acid, betulin, betulinic acid and a variety of other minor components have been identified. Elderberry fruit contains quercetin, kaempferol, rutin, phenolic acids and anthocyanins. Elderberry also contains flavonoids, which have antioxidant properties that can help prevent cellular damages, and anthocyanidins, chemical compounds that are known to have immunostimulant effects.

The raw berries are made up of 80 percent water, 18 percent carbohydrates, and less than 1 percent each of protein and fat. Elderberries are naturally high in vitamin C, vitamin A, vitamin B6, iron and potassium, among other essential nutrients.

9 Health Benefits of Elderberry

1. For Cold and Flu Relief 

Elderberries are an excellent general immune system booster. The berries contain chemical compounds called anthocyanidins, which are known to have immunostimulant effects. Is elderberry good for a cold? Research actually shows that elderberry extract is a safe, efficient and cost-effective treatment for both cold and flu symptoms.

A 2016 study published in Nutrients showed that elderberry supplementation can reduce the duration and symptoms of a cold in air travelers. Travelers using this herb from 10 days before travel until four to five days after arriving overseas experienced, on average, a two-day shorter duration of their colds and also a noticeable reduction in cold symptoms. (4)

Several studies have demonstrated that elder extract is highly effective in mitigating flu-like symptoms. Specifically, the flavonoids in the elderberry extract bind to the H1N1 human influenza virus as well as the H5N1 avian influenza virus.

A 2009 study randomized patients into two groups: One group was given four doses of 175-milligram proprietary elderberry extract daily, and the other group received a placebo daily for two days. The extract-treated group showed significant improvement in most flu symptoms, while the placebo group showed no improvement or an increase in severity of symptoms. Researchers conclude that the extract is effective in controlling influenza symptoms. (5)

Another study published in the Journal of International Medical Researchshowed that when the extract is used within the first 48 hours of the onset of flu symptoms, it shortens the duration of flu symptoms by an average of four days. (6)

2. Sinus Infection Aid

With elderberry’s anti-inflammatory and antioxidant properties, it makes sense that it can help sinus issues. A sinus infection is a condition in which the cavities around the nasal passages become inflamed, and this antiviral herb has promise as a sinus infection natural remedy.

A study conducted by the Institute of Complementary Medicine’s Department of Internal Medicine at the University Hospital in Zurich, Switzerland examined the use of a proprietary product, Sinupret, which contains elderberry flowers. The researchers used Sinupret to treat bacterial sinusitis along with an antibiotic (doxycycline or vibramycin) and a decongestant. People who took the combination did better compared to those who did not take Sinupret at all. (7)

3. Lower Blood Sugar

Both the elder flower and the berry have traditionally been used to treat diabetes. Research has confirmed that extracts of elderflower stimulate glucose metabolism and the secretion of insulin, lowering blood sugar levels.

Research published in the Journal of Nutrition evaluated black elderberry’s insulin-like and insulin-releasing actions in vitro. The study found that an aqueous extract of elder significantly increased glucose transport, glucose oxidation and glycogenesis without any added insulin. (8) What is glycogenesis, and why is it important? Glycogenesis is the process by which excess sugar is cleared out of the bloodstream and into your muscles and liver, which helps maintain normal blood sugar.

And a 2017 animal study published in the International Journal of Molecular Sciences suggests that elderberries can serve as a potential source of bioactive compounds for formulations that are used for the management of diabetes. Researchers found that both lipophilic and polar extracts of elderberry lowered insulin resistance in wistar rats with type 2 diabetes. (9)

4. Natural Diuretic

Elder has been shown to promote both urination and bowel moments. Studies have indicated that elderberry or Sambucus has natural diureticeffects. (10) A diuretic is a substance that promotes the production of urine. Doctors prescribe diuretics when the body is retaining too much fluid, which is a common problem in older adults.

5. Natural Laxative

Elderberry may also help with constipation. A small, randomized trial looked at a compound commonly used in Brazil to treat constipation. The compound contains elderberry. The results of the study indicate that this elder-centric remedy is an effective natural laxative for the treatment of constipation. Unfortunately, there are currently no studies isolating elderberry itself for constipation relief, so more research is needed. (11)

6. Encourage Healthy Skin

Elderberry has made its way into cosmetic products, and for good reason. Its bioflavonoids and antioxidants, along with its high vitamin A content, make it awesome for skin health. Researchers suspect that a compound found in the elderberry could give a natural boost to skin. (12)

A compound found in elderberry, called anthocyanin, has proven to have anti-inflammatory and antioxidant properties. Researchers found that this compound may improve the skin’s structure and condition. (12)

7. Ease Allergies

The flowers of the elder plant are known to be an effective herbal allergy remedy. Since allergies involve an overreaction of the immune system as well as inflammation, elderberry’s ability to improve the immune system and calm inflammation can help provide allergy relief.

Some herbalists put black elder flower on the list of most effective herbsused for treating hay fever-like symptoms. It can be used for allergies on its own or in combination with other herbs. Elderflower is also said to act as a detoxification aid by enhancing liver function. (13)

8. May Help Prevent Cancer 

Edible berry extracts like elderberry extract are rich in anthocyanins and have been shown to have a broad spectrum of therapeutic, pharmacologic and anti-carcinogenic properties. (14) Laboratory studies specifically indicate that the elderberry has some chemopreventive properties. A chemopreventive inhibits, delays or reverses cancer formation.

One study published in the Journal of Medicinal Food compared the anticancer properties of European and American elderberry fruits. European elderberry (Sambucus nigra) is known for its medicinal use and contains anthocyanins, flavonoids and other polyphenolics, which all contribute to the high-antioxidant capacity of its berries. American elderberry (Sambucuscanadensis) has not been grown or promoted as a medicinal plant like its European relative.

This study took extracts of both berries and tested them to access anticancer potential. Both extracts demonstrated significant chemopreventive potential. Additionally, the American elder extract showed inhibition of ornithine decarboxylase, which is an enzyme marker related to the promotion stage of cancer formation. (15) These findings indicate the potential as a natural cancer treatment option.

9. May Improve Heart Health

Although the studies in this field have found mixed results, there is research suggesting that elderberry extract may improve cardiovascular health. When mice with high cholesterol and HDL cholesterol dysfunction were given anthocyanin-rich black elderberry extract, they had a reduction in hepatic cholesterol levels with improvement in HDL function. This may be due to the presence of anthocyanins, which are polyphenols found in elderberry that have demonstrated antioxidant and anti-inflammatory activities. (16)

And another study found that elderberry extract may have beneficial effects on high blood pressure. When polyphenols extracted from the elderberry plant were given to rats with hypertension, in combination with renin inhibitors, they reduced arterial pressure. Researchers suggest that using polyphenols, like those found in elderberry, to lower blood pressure may also help to reduce the side effects of antihypertensive agents and improve patient quality of life. (17)

How to Use Elderberry

Elderberry can be purchased in many forms at your local health store or online.

14 Ways to Consume Elderberry

  • Tea
  • Wine
  • Juice
  • Jelly and jams
  • Syrup
  • Ointments
  • Astringent
  • Infusions
  • Sprays
  • Lozenges
  • Pills
  • Liquid
  • Powder
  • Capsules

When it comes to colds, flu and upper respiratory issues, elderberry syrup is very popular. There are high-quality brands readily available for purchase, or you can try making your own.

Elderberry tea is another great option. You can either buy teabags or you can purchase dried berries or flowers and make a tea by combining 1 tablespoon of berries or flowers with 8 ounces of water.

Not a fan of hot teas? Then you can try elderberry juice, which is sweet, tart and refreshing. Just watch out that you don’t purchase one that has too much added sugar.

History of Elderberry

Historically, elderberry is known as a cure-all and has been called “the medicine chest of country people.”

The Romans created hair dye from the juice. The wood of an elderberry tree is fine-grained so it polishes easily and has been used historically to make combs, toys, skewers for butchers, pegs for shoemakers and needles for weaving musical instruments.

Native Americans used the plant for healing through medicines, foods, beverages, charms, ceremonial items, inks, dyes, body paint, jewelry, hunting whistles and musical instruments.

During the 1995 Panama flu epidemic, the government employed its use to fight the flu. The berry’s juice greatly reduced the time of the flu as well as the severity, thus helping end the epidemic.

Elderberry Side Effects and Precautions

Ripe, cooked berries of most of the Sambucus species are edible. However, you should not consume raw berries or other parts of the plant since they contain a cyanide-inducing chemical. Eating uncooked berries can result in diarrhea and vomiting. Generally, commercial preparations don’t cause adverse reactions at recommended dosages.

What are the side effects of elderberry? Elderberry appears to have few side effects when used properly for short periods of time (up to five days). Occasionally, elderflowers and elderberries cause allergic reactions. Discontinue use if you have a mild allergic reaction, and seek medical attention if you have a serious allergic reaction.

You should not give elderberry products to a child before consulting your pediatrician. If you’re pregnant or breastfeeding, don’t take it.

If you have an autoimmune disease, such as rheumatoid arthritis, ask your doctor before taking elderberry because it may stimulate the immune system. If you have any other ongoing health concern, speak with your healthcare provider before taking it as well. People with organ transplants should not take elderberry.

If you currently take any of the following medications, you should talk to your healthcare provider before taking any elder plant products:

  • Diabetes medications
  • Diuretics (water pills)
  • Chemotherapy
  • Immune-suppressing drugs, including corticosteroids (prednisone), and medications used to treat autoimmune diseases
  • Laxatives
  • Theophylline (TheoDur)

Elderberry Final Thoughts 

  • What are the benefits of elderberry? For one thing, it has shown to seriously combat the common cold as well as the flu. Science has actually shown it can shorten flu symptoms by an average of four days.
  • Are elderberries poisonous to humans? No — there are actually many options when it comes to how you can consume elderberries, from juice to tea to jam. When taken properly, it typically has no negative side effects. In fact, researchers say its low cost, lack of side effects and clinical results make it an important tool for fighting flu. (18)
  • One of the most popular ways to take elderberry, especially for a cold or flu, is a syrup, which is relatively easy to make at home.
  • Research is showing its potential ability to fight cancer, and hopefully more research is coming soon. It’s also been shown to help lower blood sugar, ease allergies and improve cardiovascular health.
  • Elderberry has a pleasant berry flavor, and most people find it easy to take elder plant products.
  • Nutritional treatment offered by Steven B. Wasserman, a local Chiropractor in Los Alamitos, Dr. Wasserman can provide a consultation to identify the source or cause of your problem and a treatment plan to relieve it. Call us at 562-430-4949 for an appointment.


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